Microscale generation of cardiospheres promotes robust enrichment of cardiomyocytes derived from human pluripotent stem cells. Nguyen DC, Hookway TA, Wu Q, Jha R, Preininger MK, Chen X, Easley CA, Spearman P, Deshpande SR, Maher K, et al. Microscale generation of cardiospheres promotes robust enrichment of cardiomyocytes derived from human pluripotent stem cells. Stem Cell Reports. 2014 .
Fluid shear stress pre-conditioning promotes endothelial morphogenesis of embryonic stem cells within embryoid bodies. Nsiah BA, Ahsan T, Griffiths S, Cooke MT, Nerem RM, McDevitt TC. Fluid shear stress pre-conditioning promotes endothelial morphogenesis of embryonic stem cells within embryoid bodies. Tissue Engineering Part A. 2014 .
Temporal modulation of β-catenin signaling by multicellular aggregation kinetics impacts embryonic stem cell cardiomyogenesis. Kinney MA, Sargent CY, McDevitt TC. Temporal modulation of β-catenin signaling by multicellular aggregation kinetics impacts embryonic stem cell cardiomyogenesis. Stem Cells and Development. 2013 .
Systematic engineering of 3D pluripotent stem cell niches to guide blood development. Purpura KA, Bratt-Leal AM, Hammersmith KA, McDevitt TC, Zandstra PW. Systematic engineering of 3D pluripotent stem cell niches to guide blood development. Biomaterials. 2012 .
Magnetic manipulation and spatial patterning of multi-cellular stem cell aggregates. Bratt-Leal AM, Kepple KL, Carpenedo RL, Cooke MT, McDevitt TC. Magnetic manipulation and spatial patterning of multi-cellular stem cell aggregates. Integrative Biology. 2011 .
Microsphere size effects on embryoid body incorporation and embryonic stem cell differentiation. Carpenedo RL, Seaman SA, McDevitt TC. Microsphere size effects on embryoid body incorporation and embryonic stem cell differentiation. Journal of Biomedical Materials Research Part A. 2010 .
Hydrodynamic modulation of embryonic stem cell differentiation by rotary orbital suspension culture. Sargent CY, Berguig GY, Kinney MA, Hiatt LA, Carpenedo RL, R Berson E, McDevitt TC. Hydrodynamic modulation of embryonic stem cell differentiation by rotary orbital suspension culture. Biotechnology and Bioengineering. 2010 .
Cardiomyogenic differentiation of embryoid bodies is promoted by rotary orbital suspension culture. Sargent CY, Berguig GY, McDevitt TC. Cardiomyogenic differentiation of embryoid bodies is promoted by rotary orbital suspension culture. Tissue Engineering Part A. 2009 .
Acellularization of embryoid bodies via physical disruption methods. Ngangan AV, McDevitt TC. Acellularization of embryoid bodies via physical disruption methods. Biomaterials. 2009 .
Innovation in the culture and derivation of pluripotent human stem cells. McDevitt TC, Palecek SP. Innovation in the culture and derivation of pluripotent human stem cells. Current Opinion in Biotechnology. 2008 .
Rotary suspension culture enhances the efficiency, yield, and homogeneity of embryoid body differentiation. Carpenedo RL, Sargent CY, McDevitt TC. Rotary suspension culture enhances the efficiency, yield, and homogeneity of embryoid body differentiation. Stem Cells. 2007 .
Proliferation of cardiomyocytes derived from human embryonic stem cells is mediated via the IGF/PI 3-kinase/Akt signaling pathway. McDevitt TC, Laflamme MA, Murry CE. Proliferation of cardiomyocytes derived from human embryonic stem cells is mediated via the IGF/PI 3-kinase/Akt signaling pathway. Journal of Molecular and Cellular Cardiology. 2005 .
Spatially organized layers of cardiomyocytes on biodegradable polyurethane films for myocardial repair. McDevitt TC, Woodhouse KA, Hauschka SD, Murry CE, Stayton PS. Spatially organized layers of cardiomyocytes on biodegradable polyurethane films for myocardial repair. Journal of Biomedical Materials Research Part A. 2003 .
Structural characterization and comparison of RGD cell-adhesion recognition sites engineered into streptavidin. Le Trong I, McDevitt TC, Nelson KE, Stayton PS, Stenkamp RE. Structural characterization and comparison of RGD cell-adhesion recognition sites engineered into streptavidin. Acta Crystallographica Section D. 2003 .
Micro-scale cell patterning on non-fouling plasma polymerized tetraglyme coatings by protein microcontact printing. Y. Pan V, McDevitt TC, Kim TKyun, Leach-Scampavia D, Stayton PS, Denton DD, Ratner BD. Micro-scale cell patterning on non-fouling plasma polymerized tetraglyme coatings by protein microcontact printing. Plasmas and Polymers. 2002 .
In vitro generation of differentiated cardiac myofibers on micropatterned laminin surfaces. McDevitt TC, Angello JC, Whitney ML, Reinecke H, Hauschka SD, Murry CE, Stayton PS. In vitro generation of differentiated cardiac myofibers on micropatterned laminin surfaces. Journal of Biomedical Materials Research Part A. 2002 .
Quantitative interrogation of micropatterned biomolecules by surface force microscopy. Garrison MD, McDevitt TC, Luginbühl R, Giachelli CM, Stayton PS, Ratner BD. Quantitative interrogation of micropatterned biomolecules by surface force microscopy. Ultramicroscopy. 2000 .
Smart and biofunctional streptavidin. Stayton PS, Nelson KE, McDevitt TC, Bulmus V, Shimoboji T, Ding Z, Hoffman AS. Smart and biofunctional streptavidin. Biomolecular Engineering. 1999 .
Constrained cell recognition peptides engineered into streptavidin. McDevitt TC, Nelson KE, Stayton PS. Constrained cell recognition peptides engineered into streptavidin. Biotechnology Progress. 1999 .
Regenerating the Heart: Stem Cells and the Cardiovascular System: Regenerating Function In Vivo with Myocytes Derived from Embryonic Stem Cells. Baraniak PR, McDevitt TC. Regenerating the Heart: Stem Cells and the Cardiovascular System: Regenerating Function In Vivo with Myocytes Derived from Embryonic Stem Cells. In: Cohen I, Gaudette G ; 2010.
Expansion and angiogenic potential of mesenchymal stem cells from patients with critical limb ischemia. Brewster L, Robinson S, Wang R, Griffiths S, Li H, Peister A, Copland I, McDevitt TC. Expansion and angiogenic potential of mesenchymal stem cells from patients with critical limb ischemia. Journal of Vascular Surgery. 2016 .
Aggregate formation and suspension culture of human pluripotent stem cells and differentiated progeny. Hookway TA, Butts JC, Lee E, Tang H, McDevitt TC. Aggregate formation and suspension culture of human pluripotent stem cells and differentiated progeny. Methods. 2016 .
Design principles for engineering of tissues from human pluripotent stem cells. Matthys OB, Hookway TA, McDevitt TC. Design principles for engineering of tissues from human pluripotent stem cells. Current Stem Cell Reports. 2016 .
Hyaluronic acid as a Macromolecular Crowding Agent for Production of Cell-derived Matrices Shendi D, Marzi J, Linthicum W, Rickards AJ, Dolivo DM, Keller S, Kauss MA, Wen Q, McDevitt TC, Dominko T, et al. Hyaluronic acid as a Macromolecular Crowding Agent for Production of Cell-derived Matrices. Acta Biomaterialia. 2019 ;100.
Single-Cell Determination of Cardiac Microtissue Structure and Function Using Light Sheet Microscopy Turaga D, Matthys OB, Hookway TA, Joy DA, Calvert M, McDevitt TC. Single-Cell Determination of Cardiac Microtissue Structure and Function Using Light Sheet Microscopy. Tissue Engineering Part C: Methods. 2020 ;26(4).
Mouse gastruloids take heart Srivastava D, McDevitt TC. Mouse gastruloids take heart. Nature Reviews Cardiology. 2021 .
Engineering Co-Emergence in Organoid Models Vasic I, McDevitt T. Engineering Co-Emergence in Organoid Models. Progress in Biomedical Engineering. 2021 .
SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19 Perez-Bermejo JA, Kang S, Rockwood SJ, Simoneau CR, Joy DA, Silva AC, Ramadoss GN, Flanigan WR, Fozouni P, Li H, et al. SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19. Science Translational Medicine. 2021 .
Developmental lineage of human pluripotent stem cell‐derived cardiac fibroblasts affects their functional phenotype Floy ME, Givens SE, Matthys OB, Mateyka TD, Kerr CM, Steinberg AB, Silva AC, Zhang J, Mei Y, Ogle BM, et al. Developmental lineage of human pluripotent stem cell‐derived cardiac fibroblasts affects their functional phenotype. The FASEB Journal. 2021 .
Co-emergence of cardiac and gut tissues promotes cardiomyocyte maturation within human iPSC-derived organoids. Silva AC, Matthys OB, Joy DA, Kauss MA, Natarajan V, Lai MH, Turaga D, Blair AP, Alexanian M, Bruneau BG, et al. Co-emergence of cardiac and gut tissues promotes cardiomyocyte maturation within human iPSC-derived organoids. Cell Stem Cell. 2021 ;(12).