Lab Overview

The McDevitt lab is focused on the engineering of innovative technologies to translate the morphogenic potential of stem cells as models of development and disease, as well to develop cellular and molecular therapies aimed to treat degenerative diseases and traumatic injuries. Learn more about the research.

Since stem cells are promising for a number of applications, the emphasis of the McDevitt Lab is on the development of technology platforms to advance therapies that span multiple diseases.

Our technologies are applicable to a wide variety of diseases, including cardiovascular, orthopedic and neurological disorders. Specific diseases that we can apply our research to include treatments for diabetes, chronic wounds, aging, arthritis and other autoimmune disorders. The McDevitt lab's work also has other applications, including wound healing, irritable bowel syndrome, epilepsy and bone regeneration to name just a few. Click here for a complete list of research and disease applications.

Videos

  • Overview of Stem Cell Engineering
  • Todd was 1 of 6 panelists that toured Europe and Asia to do an international assessment of the Stem Cell Engineering field.

News

 
These tiny versions of the heart, brain, intestine, lungs, and other organs are transforming how we research human disease and development at Gladstone and beyond.
 
The McDevitt Lab Gladstone researchers used a machine-learning approach to discover new ways of controlling the spatial organization of induced pluripotent stem cells
 
Joke van Bemmel, Alexander Merriman, David Joy, and Ariel Kauss share why National Coming Out Day is important to them.
 
Building on Shinya Yamanaka’s human induced pluripotent stem cells, Gladstone researchers are developing creative strategies to use stem cells toward understanding and treating diseases.
 
A researcher claims to have used the genome editing technique CRISPR-Cas9 to modify genes in two human embryos, which led to the birth of the first genetically edited babies.
 
Todd McDevitt and Gladstone scientists have a conversation with WIRED magazine.