Project Scientist, Kimberly-Clark
McDevitt Lab Graduate Student 2006-11
Project Title:
“Angiogenic matrices derived from embryonic stem cells”

Biography

Alyssa graduated with a B.S. degree from Tufts University in 2003 after double majoring in Chemical Engineering and Biotechnology.  As an undergrad, Alyssa conducted research in the laboratory of Dr. David L. Kaplan examining the use of barnacle adhesive as a potential medical adhesive and isolating novel proteins involved in the adhesion process.  From 2003 – 2005, Alyssa worked as a research scientist designing and developing transgenic and knockout mice in the Molecular Genetics Department at Wyeth Reseach in Andover, MA. In August 2005, Alyssa joined Dr. Todd C. McDevitt’s laboratory at Georgia Institute of Technology and is currently working on her thesis project developing embryonic acellular matrices to promote angiogenesis.

Education

Bachelor of Science, Chemical Engineering
Tufts University
2003

PhD, Bioengineering
Georgia Tech
2011

Research Interests

My research examines molecular factors produced by embryonic stem cells undergoing differentiation via embryoid body formation. I am currently focusing primarily on assessing the temporal growth factors synthesized by embryonic stem cells and retained within embryoid body microenvironments.  In conjunction with ongoing acellularization studies, I am developing several in vitro assays to assess the bioactivity of stem cell-derived molecules.

Awards

NIH Cell & Tissue Engineering Training Grant Fellowship (2006-2008)

NSF Graduate Research Fellowship, Honorable Mention (2006)

TERMIS Student Travel Award (2007) 

Ngangan AV, Waring JC, Cooke MT, Mandrycky CJ, McDevitt TC. Soluble factors secreted by differentiating embryonic stem cells stimulate exogenous cell proliferation and migration. Stem Cell Research & Therapy. 2014;.
Ngangan AV, McDevitt TC. Acellularization of embryoid bodies via physical disruption methods. Biomaterials. 2009;.
Nair R, Ngangan AV, McDevitt TC. Efficacy of solvent extraction methods for acellularization of embryoid bodies. Journal of Biomaterials Science, Polymer Edition. 2008;.