Technical Application Scientist at Irvine Scientific
McDevitt Lab Research Scientist 2012-2014
Email
Project Title:
"Influence of microenvironments on adult stem cell phenotype and expansion"

Education

Master of Engineering, Mechanical Engineering
Brunel University
2004

Engineering Doctorate (EngD), Medical Devices
University of Strathclyde
2009

Research Interests

Understanding the role of microenvironments including physical and chemical cues in influencing mesenchymal stem cell gene, protein and DNA methylation profiles.    Investigating the potential of human platelet lysate as a xeno-free alternative to animal serum. Including the response of in vitro aged and sencenscent MSC populations to hPL exposure for proliferative rejeuvenation.   

Awards

Society for Biological Engineering Conference Travel Grant - 2012

Hilton Head Conference for Regnerative Medicine Travel Award - 2011, 2012, 2013

Society for General Microbiology, International Travel Grant - 2008 

British Pharmaceutical Conference, Best Poster Presentation - 2007 

Engineering and Physical Sciences Research Council (EPSRC), EngD Fellowship - 2005 to 2009

Nsiah BA, Ahsan T, Griffiths S, Cooke MT, Nerem RM, McDevitt TC. Fluid shear stress pre-conditioning promotes endothelial morphogenesis of embryonic stem cells within embryoid bodies. Tissue Engineering Part A. 2014;.
Bongiorno T, Kazlow J, Mezencev R, Griffiths S, Olivares-Navarrete R, McDonald JF, et al. Mechanical stiffness as an improved single-cell indicator of osteoblastic human mesenchymal stem cell differentiation. Journal of Biomechanics. 2014;.
Griffiths S, Baraniak PR, Copland IB, Nerem RM, McDevitt TC. Human platelet lysate stimulates high-passage and senescent human multipotent mesenchymal stromal cell growth and rejuvenation in vitro. Cytotherapy. 2013;.